Acquisition of rifabutin resistance by a rifampicin resistant mutant of <it>Mycobacterium tuberculosis </it>involves an unusual spectrum of mutations and elevated frequency

Acquisition of rifabutin resistance by a rifampicin resistant mutant of <it>Mycobacterium tuberculosis </it>involves an unusual spectrum of mutations and elevated frequency

<p>Abstract</p> <p>Background</p> <p>Mutations in a small region of the <it>rpoB </it>gene are responsible for most rifamycin resistance in <it>Mycobacterium tuberculosis</it>. In this study we have sequentially generated resistant strains to fir...

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Bibliographic Details
Main Authors: Oskam Linda, Brown Tim J, Bergval Indra L, Schuitema Anja RJ, Anthony Richard M, Klatser Paul R
Format: Article
Language:English
Published: BMC 2005-06-01
Series:Annals of Clinical Microbiology and Antimicrobials
Online Access:http://www.ann-clinmicrob.com/content/4/1/9

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