Acquisition of rifabutin resistance by a rifampicin resistant mutant of <it>Mycobacterium tuberculosis </it>involves an unusual spectrum of mutations and elevated frequency
<p>Abstract</p> <p>Background</p> <p>Mutations in a small region of the <it>rpoB </it>gene are responsible for most rifamycin resistance in <it>Mycobacterium tuberculosis</it>. In this study we have sequentially generated resistant strains to fir...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2005-06-01
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Series: | Annals of Clinical Microbiology and Antimicrobials |
Online Access: | http://www.ann-clinmicrob.com/content/4/1/9 |