Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1.

Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1.

Bartonella T4SS effector BepC was reported to mediate internalization of big Bartonella aggregates into host cells by modulating F-actin polymerization. After that, BepC was indicated to induce host cell fragmentation, an interesting cell phenotype that is characterized by failure of rear-end retrac...

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Bibliographic Details
Main Authors: Chunyan Wang, Haoran Zhang, Jiaqi Fu, Meng Wang, Yuhao Cai, Tianyun Ding, Jiezhang Jiang, Jane E Koehler, Xiaoyun Liu, Congli Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009065

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