APOE gene-dependent BOLD responses to a breath-hold across the adult lifespan
Age and apolipoprotein E (APOE) e4 genotype are two of the strongest known risk factors for sporadic Alzheimer's disease (AD). Neuroimaging has shown hemodynamic response changes with age, in asymptomatic carriers of the APOE e4 allele, and in AD. In this study, we aimed to characterize and dif...
Main Authors: | Peter M. Rasmussen, Rasmus Aamand, Eddie Weitzberg, Michael Christiansen, Leif Østergaard, Torben E. Lund |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | NeuroImage: Clinical |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158219303055 |
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