The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes
Much effort has recently been devoted to understanding the genomics of breast cancer. In this study, the authors integrate somatic mutation data with previously published copy number aberration and gene expression information for nearly 2,500 breast cancer samples.
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2016-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms11479 |
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Article |
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DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Bernard Pereira Suet-Feung Chin Oscar M. Rueda Hans-Kristian Moen Vollan Elena Provenzano Helen A. Bardwell Michelle Pugh Linda Jones Roslin Russell Stephen-John Sammut Dana W. Y. Tsui Bin Liu Sarah-Jane Dawson Jean Abraham Helen Northen John F. Peden Abhik Mukherjee Gulisa Turashvili Andrew R. Green Steve McKinney Arusha Oloumi Sohrab Shah Nitzan Rosenfeld Leigh Murphy David R. Bentley Ian O. Ellis Arnie Purushotham Sarah E. Pinder Anne-Lise Børresen-Dale Helena M. Earl Paul D. Pharoah Mark T. Ross Samuel Aparicio Carlos Caldas |
| spellingShingle |
Bernard Pereira Suet-Feung Chin Oscar M. Rueda Hans-Kristian Moen Vollan Elena Provenzano Helen A. Bardwell Michelle Pugh Linda Jones Roslin Russell Stephen-John Sammut Dana W. Y. Tsui Bin Liu Sarah-Jane Dawson Jean Abraham Helen Northen John F. Peden Abhik Mukherjee Gulisa Turashvili Andrew R. Green Steve McKinney Arusha Oloumi Sohrab Shah Nitzan Rosenfeld Leigh Murphy David R. Bentley Ian O. Ellis Arnie Purushotham Sarah E. Pinder Anne-Lise Børresen-Dale Helena M. Earl Paul D. Pharoah Mark T. Ross Samuel Aparicio Carlos Caldas The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes Nature Communications |
| author_facet |
Bernard Pereira Suet-Feung Chin Oscar M. Rueda Hans-Kristian Moen Vollan Elena Provenzano Helen A. Bardwell Michelle Pugh Linda Jones Roslin Russell Stephen-John Sammut Dana W. Y. Tsui Bin Liu Sarah-Jane Dawson Jean Abraham Helen Northen John F. Peden Abhik Mukherjee Gulisa Turashvili Andrew R. Green Steve McKinney Arusha Oloumi Sohrab Shah Nitzan Rosenfeld Leigh Murphy David R. Bentley Ian O. Ellis Arnie Purushotham Sarah E. Pinder Anne-Lise Børresen-Dale Helena M. Earl Paul D. Pharoah Mark T. Ross Samuel Aparicio Carlos Caldas |
| author_sort |
Bernard Pereira |
| title |
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes |
| title_short |
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes |
| title_full |
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes |
| title_fullStr |
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes |
| title_full_unstemmed |
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes |
| title_sort |
somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2016-05-01 |
| description |
Much effort has recently been devoted to understanding the genomics of breast cancer. In this study, the authors integrate somatic mutation data with previously published copy number aberration and gene expression information for nearly 2,500 breast cancer samples. |
| url |
https://doi.org/10.1038/ncomms11479 |
| work_keys_str_mv |
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1721447739205615616 |
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doaj-6d0c8d9a2f0d4a168b5aa700c8e0ffba2021-05-11T10:40:45ZengNature Publishing GroupNature Communications2041-17232016-05-017111610.1038/ncomms11479The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapesBernard Pereira0Suet-Feung Chin1Oscar M. Rueda2Hans-Kristian Moen Vollan3Elena Provenzano4Helen A. Bardwell5Michelle Pugh6Linda Jones7Roslin Russell8Stephen-John Sammut9Dana W. Y. Tsui10Bin Liu11Sarah-Jane Dawson12Jean Abraham13Helen Northen14John F. Peden15Abhik Mukherjee16Gulisa Turashvili17Andrew R. Green18Steve McKinney19Arusha Oloumi20Sohrab Shah21Nitzan Rosenfeld22Leigh Murphy23David R. Bentley24Ian O. Ellis25Arnie Purushotham26Sarah E. Pinder27Anne-Lise Børresen-Dale28Helena M. Earl29Paul D. Pharoah30Mark T. Ross31Samuel Aparicio32Carlos Caldas33Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayDepartment of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Montebello, Oslo 0310, NorwayCambridge Breast Unit, Addenbrooke’s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research CentreCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayInivata, Li Ka Shing Centre, Robinson WayCambridge Breast Unit, Addenbrooke’s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research CentreCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayDepartment of Oncology, University of CambridgeCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayCambridge Breast Unit, Addenbrooke’s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research CentreIllumina, Chesterford Research Park, Little ChesterfordIllumina, Chesterford Research Park, Little ChesterfordDivision of Cancer and Stem Cells, School of Medicine, University of Nottingham and Nottingham University Hospital NHS TrustDepartment of Pathology and Molecular Medicine, Queen’s University/Kingston General HospitalDivision of Cancer and Stem Cells, School of Medicine, University of Nottingham and Nottingham University Hospital NHS TrustDepartment of Molecular Oncology, British Columbia Cancer Research CentreDepartment of Molecular Oncology, British Columbia Cancer Research CentreDepartment of Molecular Oncology, British Columbia Cancer Research CentreCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayResearch Institute in Oncology and HematologyIllumina, Chesterford Research Park, Little ChesterfordDivision of Cancer and Stem Cells, School of Medicine, University of Nottingham and Nottingham University Hospital NHS TrustCancer Division, NIHR Comprehensive Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and Research Oncology, King’s College LondonCancer Division, NIHR Comprehensive Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and Research Oncology, King’s College LondonDepartment of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Montebello, Oslo 0310, NorwayCambridge Breast Unit, Addenbrooke’s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research CentreStrangeways Research Laboratory, University of CambridgeIllumina, Chesterford Research Park, Little ChesterfordDepartment of Molecular Oncology, British Columbia Cancer Research CentreCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson WayMuch effort has recently been devoted to understanding the genomics of breast cancer. In this study, the authors integrate somatic mutation data with previously published copy number aberration and gene expression information for nearly 2,500 breast cancer samples.https://doi.org/10.1038/ncomms11479 |