Lower regional gray matter volume in the absence of higher cortical amyloid burden in late-life depression

Abstract Late-life depression (LLD) is associated with a risk of developing Alzheimer’s disease (AD). However, the role of AD-pathophysiology in LLD, and its association with clinical symptoms and cognitive function are elusive. In this study, one hundred subjects underwent amyloid positron emission...

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Bibliographic Details
Main Authors: Akihiro Takamiya, Thomas Vande Casteele, Michel Koole, François-Laurent De Winter, Filip Bouckaert, Jan Van den Stock, Stefan Sunaert, Patrick Dupont, Rik Vandenberghe, Koen Van Laere, Mathieu Vandenbulcke, Louise Emsell
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95206-0

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