Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy

Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy

Abstract Background The translocator protein (TSPO) has been identified as a positron emission tomography (PET)-visible biomarker of inflammation and promising immunotherapeutic target for the treatment of Alzheimer’s disease (AD). While TSPO ligands have been shown to reduce the accumulation of the...

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Bibliographic Details
Main Authors:	Lauren H. Fairley, Naruhiko Sahara, Ichio Aoki, Bin Ji, Tetsuya Suhara, Makoto Higuchi, Anna M. Barron
Format:	Article
Language:	English
Published:	BMC 2021-03-01
Series:	Journal of Neuroinflammation
Subjects:	Alzheimer’s disease Complement Microglia Neuroinflammation Peripheral benzodiazepine receptor Tau
Online Access:	https://doi.org/10.1186/s12974-021-02122-1

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