Capturing the perfect pose
Lipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leuk...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2021-09-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02591-3 |
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doaj-6cc5de40253e45a0ae93910dcaefed33 |
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Article |
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doaj-6cc5de40253e45a0ae93910dcaefed332021-09-12T11:12:16ZengNature Publishing GroupCommunications Biology2399-36422021-09-01411210.1038/s42003-021-02591-3Capturing the perfect poseAnam Akhtar0Communications BiologyLipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leukocytes in mouse models of colitis.https://doi.org/10.1038/s42003-021-02591-3 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Anam Akhtar |
| spellingShingle |
Anam Akhtar Capturing the perfect pose Communications Biology |
| author_facet |
Anam Akhtar |
| author_sort |
Anam Akhtar |
| title |
Capturing the perfect pose |
| title_short |
Capturing the perfect pose |
| title_full |
Capturing the perfect pose |
| title_fullStr |
Capturing the perfect pose |
| title_full_unstemmed |
Capturing the perfect pose |
| title_sort |
capturing the perfect pose |
| publisher |
Nature Publishing Group |
| series |
Communications Biology |
| issn |
2399-3642 |
| publishDate |
2021-09-01 |
| description |
Lipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leukocytes in mouse models of colitis. |
| url |
https://doi.org/10.1038/s42003-021-02591-3 |
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