The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds

Cyclophostin, the cyclipostins and the salinipostins are structurally related cyclic enolphosphate natural products. This mini review describes their isolation, synthesis and biological activities. In addition, the synthesis and biological activities of monocyclic enolphosphate and mono and bicyclic...

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Main Author: Christopher D. Spilling
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/14/2579
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spelling doaj-6cbbbd0fc9c44262bfe117008a3471fd2020-11-25T01:12:51ZengMDPI AGMolecules1420-30492019-07-012414257910.3390/molecules24142579molecules24142579The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related CompoundsChristopher D. Spilling0Department of Chemistry & Biochemistry, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USACyclophostin, the cyclipostins and the salinipostins are structurally related cyclic enolphosphate natural products. This mini review describes their isolation, synthesis and biological activities. In addition, the synthesis and biological activities of monocyclic enolphosphate and mono and bicyclic enolphosphonate analogs are presented.https://www.mdpi.com/1420-3049/24/14/2579cyclophostincyclipostinsenolphosphateenolphosphonatebicyclicmonocycliclipaseinhibitor
collection DOAJ
language English
format Article
sources DOAJ
author Christopher D. Spilling
spellingShingle Christopher D. Spilling
The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds
Molecules
cyclophostin
cyclipostins
enolphosphate
enolphosphonate
bicyclic
monocyclic
lipase
inhibitor
author_facet Christopher D. Spilling
author_sort Christopher D. Spilling
title The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds
title_short The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds
title_full The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds
title_fullStr The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds
title_full_unstemmed The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds
title_sort chemistry and biology of cyclophostin, the cyclipostins and related compounds
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2019-07-01
description Cyclophostin, the cyclipostins and the salinipostins are structurally related cyclic enolphosphate natural products. This mini review describes their isolation, synthesis and biological activities. In addition, the synthesis and biological activities of monocyclic enolphosphate and mono and bicyclic enolphosphonate analogs are presented.
topic cyclophostin
cyclipostins
enolphosphate
enolphosphonate
bicyclic
monocyclic
lipase
inhibitor
url https://www.mdpi.com/1420-3049/24/14/2579
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