Future Perspectives on the Relevance of Auditory Markers in Prodromal Parkinson's Disease

Research on auditory processing in Parkinson's disease (PD) has recently made substantial progress. At present, evidence has been found for altered auditory processing in the clinical stage of PD. The auditory alterations in PD have been demonstrated with low-cost and non-invasive assessments t...

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Main Authors: Evelien De Groote, Kim De Keyser, Patrick Santens, Durk Talsma, Annelies Bockstael, Dick Botteldooren, Miet De Letter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00689/full
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spelling doaj-6cb3cdbc544d4a44be9a6e003d7fdba62020-11-25T03:04:39ZengFrontiers Media S.A.Frontiers in Neurology1664-22952020-07-011110.3389/fneur.2020.00689520273Future Perspectives on the Relevance of Auditory Markers in Prodromal Parkinson's DiseaseEvelien De Groote0Kim De Keyser1Patrick Santens2Durk Talsma3Annelies Bockstael4Dick Botteldooren5Miet De Letter6Department of Rehabilitation Sciences, Ghent University, Ghent, BelgiumDepartment of Rehabilitation Sciences, Ghent University, Ghent, BelgiumDepartment of Neurology, Ghent University Hospital, Ghent, BelgiumDepartment of Experimental Psychology, Ghent University, Ghent, BelgiumDepartment of Information Technology, INTEC, Acoustics Research Group, Ghent University, Ghent, BelgiumDepartment of Information Technology, INTEC, Acoustics Research Group, Ghent University, Ghent, BelgiumDepartment of Rehabilitation Sciences, Ghent University, Ghent, BelgiumResearch on auditory processing in Parkinson's disease (PD) has recently made substantial progress. At present, evidence has been found for altered auditory processing in the clinical stage of PD. The auditory alterations in PD have been demonstrated with low-cost and non-invasive assessments that are already used in routine clinical practice. Since auditory alterations have been reported early in disease progression, it would be highly relevant to investigate whether auditory markers could be provided in the prodromal stage of PD. In addition, auditory alterations in early stage PD might be modulated by dopaminergic medication. Therefore, the aim of this review is (1) to summarize the literature on auditory processing in PD with a specific focus on the early disease stages, (2) to give future perspectives on which audiological and electrophysiological measurements could be useful in the prodromal stage of PD and (3) to assess the effect of dopaminergic medication on potential auditory markers in the prodromal stage of PD.https://www.frontiersin.org/article/10.3389/fneur.2020.00689/fullParkinson's diseaseauditory processingprodromal markersaudiometryotoacoustic emissionsdichotic listening
collection DOAJ
language English
format Article
sources DOAJ
author Evelien De Groote
Kim De Keyser
Patrick Santens
Durk Talsma
Annelies Bockstael
Dick Botteldooren
Miet De Letter
spellingShingle Evelien De Groote
Kim De Keyser
Patrick Santens
Durk Talsma
Annelies Bockstael
Dick Botteldooren
Miet De Letter
Future Perspectives on the Relevance of Auditory Markers in Prodromal Parkinson's Disease
Frontiers in Neurology
Parkinson's disease
auditory processing
prodromal markers
audiometry
otoacoustic emissions
dichotic listening
author_facet Evelien De Groote
Kim De Keyser
Patrick Santens
Durk Talsma
Annelies Bockstael
Dick Botteldooren
Miet De Letter
author_sort Evelien De Groote
title Future Perspectives on the Relevance of Auditory Markers in Prodromal Parkinson's Disease
title_short Future Perspectives on the Relevance of Auditory Markers in Prodromal Parkinson's Disease
title_full Future Perspectives on the Relevance of Auditory Markers in Prodromal Parkinson's Disease
title_fullStr Future Perspectives on the Relevance of Auditory Markers in Prodromal Parkinson's Disease
title_full_unstemmed Future Perspectives on the Relevance of Auditory Markers in Prodromal Parkinson's Disease
title_sort future perspectives on the relevance of auditory markers in prodromal parkinson's disease
publisher Frontiers Media S.A.
series Frontiers in Neurology
issn 1664-2295
publishDate 2020-07-01
description Research on auditory processing in Parkinson's disease (PD) has recently made substantial progress. At present, evidence has been found for altered auditory processing in the clinical stage of PD. The auditory alterations in PD have been demonstrated with low-cost and non-invasive assessments that are already used in routine clinical practice. Since auditory alterations have been reported early in disease progression, it would be highly relevant to investigate whether auditory markers could be provided in the prodromal stage of PD. In addition, auditory alterations in early stage PD might be modulated by dopaminergic medication. Therefore, the aim of this review is (1) to summarize the literature on auditory processing in PD with a specific focus on the early disease stages, (2) to give future perspectives on which audiological and electrophysiological measurements could be useful in the prodromal stage of PD and (3) to assess the effect of dopaminergic medication on potential auditory markers in the prodromal stage of PD.
topic Parkinson's disease
auditory processing
prodromal markers
audiometry
otoacoustic emissions
dichotic listening
url https://www.frontiersin.org/article/10.3389/fneur.2020.00689/full
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