Exploring the relationship between serum Vitamin D and shift work

• Main Authors: Zhe-Yu Yang, Chung-Ching Wang, Ying-Jen Chen, Chia-Kuang Tsai, Peng-Fei Li, Tao-Chun Peng, Yu-Shan Sun, Wei-Liang Chen
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2021-01-01
• Series: Journal of Medical Sciences
• Subjects: shift work; 25-hydroxyvitamin d; long working hours
• Online Access: http://www.jmedscindmc.com/article.asp?issn=1011-4564;year=2021;volume=41;issue=4;spage=179;epage=185;aulast=Yang

Background: Vitamin D deficiency became increasingly common worldwide and was related to various disorders. However, there was little information concerning the relationship between serum 25-hydroxyvitamin D (25(OH) D) level and shift work. The aim of this paper was to investigate the relation between serum 25(OH) D level and shift work in the American citizens. Methods: From the 2005–2006 NHANES, a total of 3025 participants were included. The relation between serum 25(OH) D level and shift work was investigated through the regression models. Results: There was an inverse relationship between serum 25(OH) D level and female shift worker in the fully adjusted models (β coefficient = −8.774, 95% confidence intervals [CI] = −16.83–−0.71, P = 0.03). Additionally, a negative correlation was presented between serum 25OHD level and Mexican American (β coefficient = −9.825, 95% CI = −19.31–−0.33, P = 0.04). No significant differences in serum 25(OH) D level were presented among indoor/outdoor works or manual/nonmanual works. However, long working hours (>40 h/week) were remarkably correlated with low serum 25(OH) D level (β coefficient = −8.007, 95% CI = −15.32–−0.68, P = 0.03). Conclusions: Our study concluded there was an inverse correlation between serum 25(OH) D level and shift work, especially in female population.