Graph-Directed Approach for Downselecting Toxins for Experimental Structure Determination

Graph-Directed Approach for Downselecting Toxins for Experimental Structure Determination

Conotoxins are short, cysteine-rich peptides of great interest as novel therapeutic leads and of great concern as lethal biological agents due to their high affinity and specificity for various receptors involved in neuromuscular transmission. Currently, of the approximately 6000 known conotoxin seq...

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Bibliographic Details
Main Authors: Rachael A. Mansbach, Srirupa Chakraborty, Timothy Travers, S. Gnanakaran
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Marine Drugs
Subjects:
conotoxins
protein structure determination
homology modeling
network analysis
Online Access:https://www.mdpi.com/1660-3397/18/5/256

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