Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies

Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies

Antibodies are useful biomarkers and are emerging as powerful therapeutic tools. Here the authors report a rational strategy to orthogonally control assembly and disassembly of DNA-based nanostructures using specific IgG antibodies as molecular inputs.

Bibliographic Details
Main Authors: Simona Ranallo, Daniela Sorrentino, Francesco Ricci
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13104-6
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spelling doaj-6c8c61869e6448d898aa9a1560a5556a2021-05-11T11:34:11ZengNature Publishing GroupNature Communications2041-17232019-12-011011910.1038/s41467-019-13104-6Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodiesSimona Ranallo0Daniela Sorrentino1Francesco Ricci2Chemistry Department, University of Rome, Tor Vergata, Via della Ricerca ScientificaChemistry Department, University of Rome, Tor Vergata, Via della Ricerca ScientificaChemistry Department, University of Rome, Tor Vergata, Via della Ricerca ScientificaAntibodies are useful biomarkers and are emerging as powerful therapeutic tools. Here the authors report a rational strategy to orthogonally control assembly and disassembly of DNA-based nanostructures using specific IgG antibodies as molecular inputs.https://doi.org/10.1038/s41467-019-13104-6
collection DOAJ
language English
format Article
sources DOAJ
author Simona Ranallo
Daniela Sorrentino
Francesco Ricci
spellingShingle Simona Ranallo
Daniela Sorrentino
Francesco Ricci
Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
Nature Communications
author_facet Simona Ranallo
Daniela Sorrentino
Francesco Ricci
author_sort Simona Ranallo
title Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
title_short Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
title_full Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
title_fullStr Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
title_full_unstemmed Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
title_sort orthogonal regulation of dna nanostructure self-assembly and disassembly using antibodies
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-12-01
description Antibodies are useful biomarkers and are emerging as powerful therapeutic tools. Here the authors report a rational strategy to orthogonally control assembly and disassembly of DNA-based nanostructures using specific IgG antibodies as molecular inputs.
url https://doi.org/10.1038/s41467-019-13104-6
work_keys_str_mv AT simonaranallo orthogonalregulationofdnananostructureselfassemblyanddisassemblyusingantibodies
AT danielasorrentino orthogonalregulationofdnananostructureselfassemblyanddisassemblyusingantibodies
AT francescoricci orthogonalregulationofdnananostructureselfassemblyanddisassemblyusingantibodies
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