Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies

Antibodies are useful biomarkers and are emerging as powerful therapeutic tools. Here the authors report a rational strategy to orthogonally control assembly and disassembly of DNA-based nanostructures using specific IgG antibodies as molecular inputs.

Bibliographic Details
Main Authors: Simona Ranallo, Daniela Sorrentino, Francesco Ricci
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13104-6
Description
Summary:Antibodies are useful biomarkers and are emerging as powerful therapeutic tools. Here the authors report a rational strategy to orthogonally control assembly and disassembly of DNA-based nanostructures using specific IgG antibodies as molecular inputs.
ISSN:2041-1723