Platelet‐Like Fusogenic Liposome‐Mediated Targeting Delivery of miR‐21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia‐Reperfusion Injury

Platelet‐Like Fusogenic Liposome‐Mediated Targeting Delivery of miR‐21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia‐Reperfusion Injury

Abstract Inflammatory modulations focusing on macrophage phenotype are promising candidates to promote better cardiac healing post myocardial ischemia‐reperfusion (MI/R) injury. However, the peak of monocyte/macrophage recruitment is later than the time when enhanced permeability and retention effec...

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Bibliographic Details
Main Authors: Haipeng Tan, Ya'nan Song, Jing Chen, Ning Zhang, Qiaozi Wang, Qiyu Li, Jinfeng Gao, Hongbo Yang, Zheng Dong, Xueyi Weng, Zhengmin Wang, Dili Sun, Wusiman Yakufu, Zhiqing Pang, Zheyong Huang, Junbo Ge
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Advanced Science
Subjects:
Biomimetic
macrophages
membrane fusion
miRNAs
monocytes
myocardial ischemia‐reperfusion injury
Online Access:https://doi.org/10.1002/advs.202100787

Internet

https://doi.org/10.1002/advs.202100787

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