New plastic material for the treatment of vertebral pathology and not only...
The paper presents results of the author’s multi-year research in the field of cellular technologies. The differentiation stages of the chondro-osseous graft are described based on the findings of morphological, ultrastructural, and molecular genetic studies. The stages of cell transformation, dyn...
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| Format: | Article |
| Language: | English |
| Published: |
Ministry of Health of Russian Federation, Federal State Budgetary Institution "Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. Ya.L. Tsivyan"
2018-06-01
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| Series: | Хирургия позвоночника |
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| Online Access: | https://www.spinesurgery.ru/jour/article/view/1474/1416 |
| Summary: | The paper presents results of the author’s multi-year research in the field of cellular technologies. The differentiation stages of the chondro-osseous graft are described based on the findings of morphological, ultrastructural, and molecular genetic studies. The stages of cell
transformation, dynamics of synthetic processes and matrix formation are identified. Hypotheses of the histogenesis of initial stages of
different types of bone tissue, and the formation of microcirculatory and vascular beds in the process of osteogenesis are suggested. Experimental testing of regenerative potentialities of the bone graft in animals has shown that it is a primitive bone tissue with a high potency
to proliferation, formation and differentiation into definitive bone tissue within a transplant zone. |
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| ISSN: | 1810-8997 2313-1497 |