Imaging of Joints and Bones in Autoinflammation

Autoinflammatory disorders are commonly characterized by seemingly unprovoked systemic inflammation mainly driven by cells and cytokines of the innate immune system. In many disorders on this spectrum, joint and bone involvement may be observed and imaging of these manifestations can provide essenti...

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Main Authors:	Katharina Ziegeler, Iris Eshed, Torsten Diekhoff, Kay-Geert Hermann
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Series:	Journal of Clinical Medicine
Subjects:	imaging autoinflammation arthritis
Online Access:	https://www.mdpi.com/2077-0383/9/12/4074

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spelling	doaj-6c7531f36cd64d8c8dd0e9e9a9403b632020-12-18T00:02:27ZengMDPI AGJournal of Clinical Medicine2077-03832020-12-0194074407410.3390/jcm9124074Imaging of Joints and Bones in AutoinflammationKatharina Ziegeler0Iris Eshed1Torsten Diekhoff2Kay-Geert Hermann3Department of Radiology, Charité—Universitätsmedizin Berlin, 10117 Berlin, GermanyDepartment of Diagnostic Imaging, Sheba Medical Center, Tel Giborim Affiliated with the Sackler School of Medicine, Tel Aviv University, 52621 Tel Aviv, IsraelDepartment of Radiology, Charité—Universitätsmedizin Berlin, 10117 Berlin, GermanyDepartment of Radiology, Charité—Universitätsmedizin Berlin, 10117 Berlin, GermanyAutoinflammatory disorders are commonly characterized by seemingly unprovoked systemic inflammation mainly driven by cells and cytokines of the innate immune system. In many disorders on this spectrum, joint and bone involvement may be observed and imaging of these manifestations can provide essential diagnostic information. This review aimed to provide a comprehensive overview of the imaging characteristics for major diseases and disease groups on the autoinflammatory spectrum, including familial Mediterranean fever (FMF), Behçet disease (BD), crystal deposition diseases (including gout), adult-onset Still’s disease (AoSD), and syndromatic synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO)/chronic recurrent multifocal osteomyelitis (CRMO). Herein, we discuss common and distinguishing imaging characteristics, phenotypical overlaps with related diseases, and promising fields of future research.https://www.mdpi.com/2077-0383/9/12/4074imagingautoinflammationarthritis
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Katharina Ziegeler Iris Eshed Torsten Diekhoff Kay-Geert Hermann
spellingShingle	Katharina Ziegeler Iris Eshed Torsten Diekhoff Kay-Geert Hermann Imaging of Joints and Bones in Autoinflammation Journal of Clinical Medicine imaging autoinflammation arthritis
author_facet	Katharina Ziegeler Iris Eshed Torsten Diekhoff Kay-Geert Hermann
author_sort	Katharina Ziegeler
title	Imaging of Joints and Bones in Autoinflammation
title_short	Imaging of Joints and Bones in Autoinflammation
title_full	Imaging of Joints and Bones in Autoinflammation
title_fullStr	Imaging of Joints and Bones in Autoinflammation
title_full_unstemmed	Imaging of Joints and Bones in Autoinflammation
title_sort	imaging of joints and bones in autoinflammation
publisher	MDPI AG
series	Journal of Clinical Medicine
issn	2077-0383
publishDate	2020-12-01
description	Autoinflammatory disorders are commonly characterized by seemingly unprovoked systemic inflammation mainly driven by cells and cytokines of the innate immune system. In many disorders on this spectrum, joint and bone involvement may be observed and imaging of these manifestations can provide essential diagnostic information. This review aimed to provide a comprehensive overview of the imaging characteristics for major diseases and disease groups on the autoinflammatory spectrum, including familial Mediterranean fever (FMF), Behçet disease (BD), crystal deposition diseases (including gout), adult-onset Still’s disease (AoSD), and syndromatic synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO)/chronic recurrent multifocal osteomyelitis (CRMO). Herein, we discuss common and distinguishing imaging characteristics, phenotypical overlaps with related diseases, and promising fields of future research.
topic	imaging autoinflammation arthritis
url	https://www.mdpi.com/2077-0383/9/12/4074
work_keys_str_mv	AT katharinaziegeler imagingofjointsandbonesinautoinflammation AT iriseshed imagingofjointsandbonesinautoinflammation AT torstendiekhoff imagingofjointsandbonesinautoinflammation AT kaygeerthermann imagingofjointsandbonesinautoinflammation
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Imaging of Joints and Bones in Autoinflammation

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