Analysis of related factors affecting prognosis of shunt surgery in patients with secondary normal pressure hydrocephalus

• Main Authors: WANG Cheng, DU Hang-gen, YIN Li-chun, HE Min, ZHANG Guo-jun, TIAN Yong, HAO Bi-lie
• Format: Article
• Language: English
• Published: Elsevier 2013-08-01
• Series: Chinese Journal of Traumatology
• Online Access: http://www.cjtrauma.com/apps/ojs/index.php/cjt/article/view/428

【Abstract】Objective: The management of se-condary normal pressure hydrocephalus (sNPH) is controversial. Many factors may affect the surgery effect. The purpose of this study was to identify the possible fac-tors influencing prognosis and provide theoretical basis for clinical treatment of sNPH. Methods: A retrospective study was carried out to investigate the results of 31 patients with sNPH who under-went ventriculoperitoneal shunt surgery from January 2007 to December 2011. We processed the potential influencing factors by univariate analysis and the result further by mul-tivariate logistic regression analysis. Results: Factors including age, disease duration and Glasgow coma scale (GCS) score before surgery significantly influenced the prognosis of sNPH (P<0.05). Further logistic regression analysis showed that all the three factors are independent influencing factors. Conclusion: Age, disease duration and GCS score before surgery have positive predictive value in estimating favorable response to surgical treatment for sNPH. Key words: Hydrocephalus, normal pressure; Ventriculoperitoneal shunt; Regression analysis