Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases

A high serum vitamin B12 level (hypercobalaminemia) is a underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, which are related to defects in tissue uptake of vitamin B12. The increase in the level of serum cobalamin occurs mainly in serious diseases that r...

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Main Authors: V I Podzolkov, N A Dragomiretskaya, O Ts Dambaeva, S T Auvinen, I D Medvedev
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2019-08-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/33694/pdf
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spelling doaj-6c6d7a60871a415a91a534c46e0787692020-11-25T03:05:23Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422019-08-0191816016710.26442/00403660.2019.08.00037830422Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseasesV I Podzolkov0N A Dragomiretskaya1O Ts Dambaeva2S T Auvinen3I D Medvedev4Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)A high serum vitamin B12 level (hypercobalaminemia) is a underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, which are related to defects in tissue uptake of vitamin B12. The increase in the level of serum cobalamin occurs mainly in serious diseases that require early diagnosis: hemoblastosis, liver and kidney diseases, etc. This review presents data on the metabolism of vitamin B12 and the potential significance of increasing its level as a marker for the early diagnosis of these diseases.https://ter-arkhiv.ru/0040-3660/article/viewFile/33694/pdfhypervitaminosis b12hypercobalaminemiahemoblastosisliver diseases
collection DOAJ
language Russian
format Article
sources DOAJ
author V I Podzolkov
N A Dragomiretskaya
O Ts Dambaeva
S T Auvinen
I D Medvedev
spellingShingle V I Podzolkov
N A Dragomiretskaya
O Ts Dambaeva
S T Auvinen
I D Medvedev
Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases
Терапевтический архив
hypervitaminosis b12
hypercobalaminemia
hemoblastosis
liver diseases
author_facet V I Podzolkov
N A Dragomiretskaya
O Ts Dambaeva
S T Auvinen
I D Medvedev
author_sort V I Podzolkov
title Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases
title_short Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases
title_full Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases
title_fullStr Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases
title_full_unstemmed Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases
title_sort hypervitaminosis b12 - a new marker and predictor of prognostically unfavorable diseases
publisher "Consilium Medicum" Publishing house
series Терапевтический архив
issn 0040-3660
2309-5342
publishDate 2019-08-01
description A high serum vitamin B12 level (hypercobalaminemia) is a underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, which are related to defects in tissue uptake of vitamin B12. The increase in the level of serum cobalamin occurs mainly in serious diseases that require early diagnosis: hemoblastosis, liver and kidney diseases, etc. This review presents data on the metabolism of vitamin B12 and the potential significance of increasing its level as a marker for the early diagnosis of these diseases.
topic hypervitaminosis b12
hypercobalaminemia
hemoblastosis
liver diseases
url https://ter-arkhiv.ru/0040-3660/article/viewFile/33694/pdf
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AT nadragomiretskaya hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases
AT otsdambaeva hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases
AT stauvinen hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases
AT idmedvedev hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases
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