Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases
A high serum vitamin B12 level (hypercobalaminemia) is a underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, which are related to defects in tissue uptake of vitamin B12. The increase in the level of serum cobalamin occurs mainly in serious diseases that r...
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2019-08-01
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doaj-6c6d7a60871a415a91a534c46e0787692020-11-25T03:05:23Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422019-08-0191816016710.26442/00403660.2019.08.00037830422Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseasesV I Podzolkov0N A Dragomiretskaya1O Ts Dambaeva2S T Auvinen3I D Medvedev4Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)A high serum vitamin B12 level (hypercobalaminemia) is a underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, which are related to defects in tissue uptake of vitamin B12. The increase in the level of serum cobalamin occurs mainly in serious diseases that require early diagnosis: hemoblastosis, liver and kidney diseases, etc. This review presents data on the metabolism of vitamin B12 and the potential significance of increasing its level as a marker for the early diagnosis of these diseases.https://ter-arkhiv.ru/0040-3660/article/viewFile/33694/pdfhypervitaminosis b12hypercobalaminemiahemoblastosisliver diseases |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
V I Podzolkov N A Dragomiretskaya O Ts Dambaeva S T Auvinen I D Medvedev |
spellingShingle |
V I Podzolkov N A Dragomiretskaya O Ts Dambaeva S T Auvinen I D Medvedev Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases Терапевтический архив hypervitaminosis b12 hypercobalaminemia hemoblastosis liver diseases |
author_facet |
V I Podzolkov N A Dragomiretskaya O Ts Dambaeva S T Auvinen I D Medvedev |
author_sort |
V I Podzolkov |
title |
Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases |
title_short |
Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases |
title_full |
Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases |
title_fullStr |
Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases |
title_full_unstemmed |
Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases |
title_sort |
hypervitaminosis b12 - a new marker and predictor of prognostically unfavorable diseases |
publisher |
"Consilium Medicum" Publishing house |
series |
Терапевтический архив |
issn |
0040-3660 2309-5342 |
publishDate |
2019-08-01 |
description |
A high serum vitamin B12 level (hypercobalaminemia) is a underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, which are related to defects in tissue uptake of vitamin B12. The increase in the level of serum cobalamin occurs mainly in serious diseases that require early diagnosis: hemoblastosis, liver and kidney diseases, etc. This review presents data on the metabolism of vitamin B12 and the potential significance of increasing its level as a marker for the early diagnosis of these diseases. |
topic |
hypervitaminosis b12 hypercobalaminemia hemoblastosis liver diseases |
url |
https://ter-arkhiv.ru/0040-3660/article/viewFile/33694/pdf |
work_keys_str_mv |
AT vipodzolkov hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases AT nadragomiretskaya hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases AT otsdambaeva hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases AT stauvinen hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases AT idmedvedev hypervitaminosisb12anewmarkerandpredictorofprognosticallyunfavorablediseases |
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