9.5 COAGULATION CONTROL BY THE RHOA PATHWAY AND THE EXCHANGE FACTOR ARHGEF1
Platelet activation by thrombin is an auto-amplification loop of thrombin generation, a major factor in the formation of atherosclerotic plaques. The small G protein RhoA, under the direct control of the exchange factor Arhgef1, modulates several cellular functions in inflammation. The objective was...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Atlantis Press
2016-11-01
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| Series: | Artery Research |
| Online Access: | https://www.atlantis-press.com/article/125930433/view |