Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system

Legionella pneumophila employs the Type 4B secretion system (T4BSS) to translocate more than 300 effector proteins into the host cell during infection. Here the authors present the crystal structure of the DotM soluble domain and give mechanistic insights into the recruitment of Glu-rich motif-conta...

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Bibliographic Details
Main Authors: Amit Meir, David Chetrit, Luying Liu, Craig R. Roy, Gabriel Waksman
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02578-x