Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model
The marked increase in the incidence of melanoma coupled with the rapid drop in the survival rate after metastasis has promoted the investigation into improved diagnostic methods for melanoma. High-frequency ultrasound (US), optical coherence tomography (OCT), and photoacoustic imaging (PAI) are thr...
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MDPI AG
2019-06-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/19/12/2815 |
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doaj-6c5f1cdf2a0e432d9993823852cf1d732020-11-24T23:55:37ZengMDPI AGSensors1424-82202019-06-011912281510.3390/s19122815s19122815Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine ModelKarl Kratkiewicz0Rayyan Manwar1Ali Rajabi-Estarabadi2Joseph Fakhoury3Jurgita Meiliute4Steven Daveluy5Darius Mehregan6Kamran (Mohammad) Avanaki7Department of Biomedical Engineering, Wayne State University, Detroit, MI 48201, USADepartment of Biomedical Engineering, Wayne State University, Detroit, MI 48201, USADr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, USAWayne State University School of Medicine, Detroit, MI 48201, USAEKSPLA USA, Bozeman, MT 59715, USADepartment of Neurology, Wayne State University School of Medicine, Detroit, MI 48201, USAWayne State University School of Medicine, Detroit, MI 48201, USADepartment of Biomedical Engineering, Wayne State University, Detroit, MI 48201, USAThe marked increase in the incidence of melanoma coupled with the rapid drop in the survival rate after metastasis has promoted the investigation into improved diagnostic methods for melanoma. High-frequency ultrasound (US), optical coherence tomography (OCT), and photoacoustic imaging (PAI) are three potential modalities that can assist a dermatologist by providing extra information beyond dermoscopic features. In this study, we imaged a swine model with spontaneous melanoma using these modalities and compared the images with images of nearby healthy skin. Histology images were used for validation.https://www.mdpi.com/1424-8220/19/12/2815photoacoustic imagingcancer imagingskin imagingultrasoundoptical coherence tomographymelanomaswine melanoma model |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Karl Kratkiewicz Rayyan Manwar Ali Rajabi-Estarabadi Joseph Fakhoury Jurgita Meiliute Steven Daveluy Darius Mehregan Kamran (Mohammad) Avanaki |
| spellingShingle |
Karl Kratkiewicz Rayyan Manwar Ali Rajabi-Estarabadi Joseph Fakhoury Jurgita Meiliute Steven Daveluy Darius Mehregan Kamran (Mohammad) Avanaki Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model Sensors photoacoustic imaging cancer imaging skin imaging ultrasound optical coherence tomography melanoma swine melanoma model |
| author_facet |
Karl Kratkiewicz Rayyan Manwar Ali Rajabi-Estarabadi Joseph Fakhoury Jurgita Meiliute Steven Daveluy Darius Mehregan Kamran (Mohammad) Avanaki |
| author_sort |
Karl Kratkiewicz |
| title |
Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model |
| title_short |
Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model |
| title_full |
Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model |
| title_fullStr |
Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model |
| title_full_unstemmed |
Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model |
| title_sort |
photoacoustic/ultrasound/optical coherence tomography evaluation of melanoma lesion and healthy skin in a swine model |
| publisher |
MDPI AG |
| series |
Sensors |
| issn |
1424-8220 |
| publishDate |
2019-06-01 |
| description |
The marked increase in the incidence of melanoma coupled with the rapid drop in the survival rate after metastasis has promoted the investigation into improved diagnostic methods for melanoma. High-frequency ultrasound (US), optical coherence tomography (OCT), and photoacoustic imaging (PAI) are three potential modalities that can assist a dermatologist by providing extra information beyond dermoscopic features. In this study, we imaged a swine model with spontaneous melanoma using these modalities and compared the images with images of nearby healthy skin. Histology images were used for validation. |
| topic |
photoacoustic imaging cancer imaging skin imaging ultrasound optical coherence tomography melanoma swine melanoma model |
| url |
https://www.mdpi.com/1424-8220/19/12/2815 |
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