Fish oil and indomethacin in combination potently reduce dyslipidemia and hepatic steatosis in LDLR −/− mice

Fish oil and indomethacin in combination potently reduce dyslipidemia and hepatic steatosis in LDLR −/− mice

Fish oil (FO) is a potent anti-inflammatory and lipid-lowering agent. Because inflammation can modulate lipid metabolism and vice versa, we hypothesized that combining FO with cyclooxygenase inhibitors (COXIBs), well-known anti-inflammatory drugs, can enhance the anti-inflammatory and lipid-lowering...

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Bibliographic Details
Main Authors: Ganesan Murali, Ginger L. Milne, Corey D. Webb, Ann B. Stewart, Ryan P. McMillan, Brandon C. Lyle, Matthew W. Hulver, Viswanathan Saraswathi
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Journal of Lipid Research
Subjects:
n-3 fatty acids
cytochrome P450
cholesterol
triglycerides
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520431955

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http://www.sciencedirect.com/science/article/pii/S0022227520431955

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