Conservative management of chronic venous insufficiency using flebofa drug

• Main Authors: I.G. Uchkin, E.N. Saverskaya, I.T. Khadzhishvili
• Format: Article
• Language: Russian
• Published: Remedium Group LTD 2017-12-01
• Series: Амбулаторная хирургия
• Subjects: роническая венозная недостаточность; варикозная болезнь; диосминсодержащие препараты; консервативная терапия; флебофа; chronic venous insufficiency; varicose disease; diosmin-containing drugs; conservative management; flebofa
• Online Access: https://www.a-surgeon.ru/jour/article/view/85
• ISSN: 2712-8741; 2782-2591

The review presents data on the prevalence of chronic venous insufficiency (CVI) of the lower limbs. Particular attention is paid to contemporary views of the risk factors and pathogenesis of this disease. Key approaches to the CVI therapy are considered. The article provides detailed information on the pharmacological effects of flavonoids, in particular, diosmin. It also provides data on the clinical efficacy and safety of a highly purified diosmin and the results of a comparative study of the therapeutic equivalence of the domestic drug Flebof 600 and the original drug.