A Complex Interplay between Nitric Oxide, Quorum Sensing, and the Unique Secondary Metabolite Tundrenone Constitutes the Hypoxia Response in Methylobacter

A Complex Interplay between Nitric Oxide, Quorum Sensing, and the Unique Secondary Metabolite Tundrenone Constitutes the Hypoxia Response in Methylobacter

Here, we describe a novel and complex hypoxia response system in a methanotrophic bacterium that involves modules of central carbon metabolism, denitrification, quorum sensing, and a secondary metabolite, tundrenone. This intricate stress response system, so far unique to Methylobacter species, may...

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Bibliographic Details
Main Authors: Zheng Yu, Mitchell Pesesky, Lei Zhang, Jing Huang, Mari Winkler, Ludmila Chistoserdova
Format: Article
Language:English
Published: American Society for Microbiology 2020-01-01
Series:mSystems
Subjects:
hypoxia
methylobacter tundripaludum
nitric oxide
hybrid cluster protein
quorum sensing
tundrenone
Online Access:https://doi.org/10.1128/mSystems.00770-19

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