Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis
Engineering dynamic control can improve microbial production of target chemicals. Here, the authors design a sensor-regulator and RNAi based bifunctional dynamic control network that can simultaneously and independently turn up and down cellular metabolism for engineered muconic acid production in E...
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Bibliographic Details
Main Authors: |
Yaping Yang,
Yuheng Lin,
Jian Wang,
Yifei Wu,
Ruihua Zhang,
Mengyin Cheng,
Xiaolin Shen,
Jia Wang,
Zhenya Chen,
Chenyi Li,
Qipeng Yuan,
Yajun Yan |
Format: | Article
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Language: | English |
Published: |
Nature Publishing Group
2018-08-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-018-05466-0
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