A Long-Awaited Structure Is Rev-ealed

It has been known for some time that the HIV Rev protein binds and oligomerizes on a well-defined multiple stem-loop RNA structure, named the Rev Response Element (RRE), which is present in a subset of HIV mRNAs. This binding is the first step in a pathway that overcomes a host restriction, which wo...

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Bibliographic Details
Main Authors: Marie-Louise Hammarskjold, David Rekosh
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Viruses
Subjects:
Rev
RRE
Online Access:http://www.mdpi.com/1999-4915/3/5/484/