Adverse Impact of Heavy Metals on Bone Cells and Bone Metabolism Dependently and Independently through Anemia

Adverse Impact of Heavy Metals on Bone Cells and Bone Metabolism Dependently and Independently through Anemia

Abstract Mounting evidence is revealing that heavy metals can incur disordered bone homeostasis, leading to the development of degenerative bone diseases, including osteoporosis, osteoarthritis, degenerative disk disease, and osteomalacia. Meanwhile, heavy metal‐induced anemia has been found to be i...

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Bibliographic Details
Main Authors: Shuping Zhang, Li Sun, Jie Zhang, Sijin Liu, Jinxiang Han, Yajun Liu
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Advanced Science
Subjects:
heavy metals
degenerative bone diseases
anemia
adverse outcome pathways
mode of actions
Online Access:https://doi.org/10.1002/advs.202000383

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