Model-based assessment of replicability for genome-wide association meta-analysis
In genome-wide association meta-analysis, it is often difficult to find an independent dataset of sufficient size to replicate associations. Here, the authors have developed MAMBA to calculate the probability of replicability based on consistency between datasets within the meta-analysis.
Bibliographic Details
| Main Authors: |
Daniel McGuire,
Yu Jiang,
Mengzhen Liu,
J. Dylan Weissenkampen,
Scott Eckert,
Lina Yang,
Fang Chen,
GWAS and Sequencing Consortium of Alcohol and Nicotine Use (GSCAN),
Arthur Berg,
Scott Vrieze,
Bibo Jiang,
Qunhua Li,
Dajiang J. Liu |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2021-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-21226-z
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