Sub-inhibitory concentrations of oxacillin modify the expression of agr locus in Staphylococcus aureus clinical strains belonging to different clonal complexes

Sub-inhibitory concentrations of oxacillin modify the expression of agr locus in Staphylococcus aureus clinical strains belonging to different clonal complexes

Abstract Background The ability of Staphylococcus aureus to invade tissues and cause an infectious disease is the result of a multi-factorial process supported by the huge number of virulence factors inherent to this microorganism tightly regulated by the accessory gene regulator (agr). During antim...

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Bibliographic Details
Main Authors: Esther Viedma, Dafne Pérez-Montarelo, Jennifer Villa, Irene Muñoz-Gallego, Nieves Larrosa, Nuria Fernández-Hidalgo, Joan Gavaldà, Benito Almirante, Fernando Chaves
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Infectious Diseases
Subjects:
Staphylococcus aureus
Oxacillin
Sub-inhibitory concentrations
agr locus expression
agr mutations
Clonal complex
Online Access:http://link.springer.com/article/10.1186/s12879-018-3088-7

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