Neocentromeres form efficiently at multiple possible loci in Candida albicans.
Centromeres are critically important for chromosome stability and integrity. Most eukaryotes have regional centromeres that include long tracts of repetitive DNA packaged into pericentric heterochromatin. Neocentromeres, new sites of functional kinetochore assembly, can form at ectopic loci because...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-03-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2642679?pdf=render |