Mechanistic modelling of a recombinase-based two-input temporal logic gate

Mechanistic modelling of a recombinase-based two-input temporal logic gate

Site-specific recombinases (SSRs) mediate efficient manipulation of DNA sequences in vitro and in vivo. In particular, serine integrases have been identified as highly effective tools for facilitating DNA inversion, enabling the design of genetic switches that are capable of turning the expression o...

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Bibliographic Details
Main Authors: Jack E. Bowyer, Victoria Hsiao, Wilson W. Wong, Declan G. Bates
Format: Article
Language:English
Published: Wiley 2017-07-01
Series:Engineering Biology
Subjects:
logic gates
enzymes
molecular biophysics
dna
boolean algebra
genetics
mechanistic modelling
recombinase-based two-input temporal logic gate
site-specific recombinases
dna sequence in vitro
dna sequence in vivo
genetic switches
serine integrases
ssr protein
biological boolean logic operations
boolean logic gates
two-input temporal logic gate circuit
serine-integrase-mediated dna inversion
Online Access:https://digital-library.theiet.org/content/journals/10.1049/enb.2017.0006

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https://digital-library.theiet.org/content/journals/10.1049/enb.2017.0006

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