LIM and SH3 protein-1 modulates CXCR2-mediated cell migration.

The chemokine receptor CXCR2 plays a pivotal role in migration of neutrophils, macrophages and endothelial cells, modulating several biological responses such as angiogenesis, wound healing and acute inflammation. CXCR2 is also involved in pathogenesis of chronic inflammation, sepsis and atheroscler...

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Bibliographic Details
Main Authors: Dayanidhi Raman, Jiqing Sai, Nicole F Neel, Catherine S Chew, Ann Richmond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2856662?pdf=render

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