Uveal melanoma cells utilize a novel route for transendothelial migration.
Uveal melanoma arises in the eye, and it spreads to distant organs in almost half of patients, leading to a fatal outcome. To metastasize, uveal melanoma cells must transmigrate into and out of the microvasculature, crossing the monolayer of endothelial cells that separates the vessel lumen from sur...
Main Authors: | Michael D Onken, Jinmei Li, John A Cooper |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4266671?pdf=render |
Similar Items
-
Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells
by: Francesco Roncato, et al.
Published: (2021-01-01) -
Transposase mapping identifies the genomic targets of BAP1 in uveal melanoma
by: Matthew Yen, et al.
Published: (2018-11-01) -
Adhesion and transendothelial migration of cancer cells
by: Sundar Rajan, Vinoth Edal Joseph
Published: (2016) -
An in vitro model of mononuclear cell transendothelial migration
by: Lidington, Elaine Alison
Published: (1998) -
Tumor cell nuclei soften during transendothelial migration
by: Roberts, Anya B, et al.
Published: (2022)