The kinetochore is an enhancer of pericentric cohesin binding.
The recruitment of cohesins to pericentric chromatin in some organisms appears to require heterochromatin associated with repetitive DNA. However, neocentromeres and budding yeast centromeres lack flanking repetitive DNA, indicating that cohesin recruitment occurs through an alternative pathway. Her...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2004-09-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.0020260 |