Switch of voltage-gated K+ channel expression in the plasma membrane of chondrogenic cells affects cytosolic Ca2+-oscillations and cartilage formation.

BACKGROUND: Understanding the key elements of signaling of chondroprogenitor cells at the earliest steps of differentiation may substantially improve our opportunities for the application of mesenchymal stem cells in cartilage tissue engineering, which is a promising approach of regenerative therapy...

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Main Authors: Zoltan Varga, Tamás Juhász, Csaba Matta, János Fodor, Éva Katona, Adam Bartok, Tamás Oláh, Attila Sebe, László Csernoch, Gyorgy Panyi, Róza Zákány
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3221679?pdf=render