Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species

Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species

<p>Abstract</p> <p>In this study, we first demonstrate that endogenous hBST-2 is predominantly expressed on the plasma membrane of a human T cell line, MT-4 cells, and that Vpu-deficient HIV-1 was less efficiently released than wild-type HIV-1 from MT-4 cells. In addition, surface...

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Bibliographic Details
Main Authors: Sato Kei, Yamamoto Seiji P, Misawa Naoko, Yoshida Takeshi, Miyazawa Takayuki, Koyanagi Yoshio
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/53

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