Knockdown of LncRNA-H19 Ameliorates Kidney Fibrosis in Diabetic Mice by Suppressing miR-29a-Mediated EndMT

Knockdown of LncRNA-H19 Ameliorates Kidney Fibrosis in Diabetic Mice by Suppressing miR-29a-Mediated EndMT

Diabetic nephropathy is the leading cause of kidney fibrosis. Recently, altered expressed or dysfunction of some long non-coding RNAs (lncRNAs) has been linked to kidney fibrosis; however, the mechanisms of lncRNAs in kidney fibrosis remain unclear. We have shown that the DPP-4 inhibitor linagliptin...

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Bibliographic Details
Main Authors:	Sen Shi, Li Song, Hao Yu, Songlin Feng, Jianhua He, Yong Liu, Yanzheng He
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Series:	Frontiers in Pharmacology
Subjects:	TGF-β/SMAD3 singling kidney fibrosis long non-coding ribonucleic acid-H19 endothelial-mesenchymal transition microRNA-29a
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2020.586895/full

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