The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies.

Liver fibrosis results from dysregulation of normal wound healing, inflammation, activation of myofibroblasts and deposition of extracellular matrix (ECM). Chronic liver injury causes death of hepatocytes and formation of apoptotic bodies, which in turn, release factors that recruit inflammatory cel...

Full description

Bibliographic Details
Main Authors: Jun eXu, Xiao eLiu, Yukinori eKoyama, Ping eWang, Tian eLan, In-Gyu eKim, In Hee eKim, Hsiao-Yen eMa, Tatiana eKisseleva
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00167/full