Phytochemicals in Gynecological Cancer Prevention

Phytochemicals in Gynecological Cancer Prevention

Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhib...

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Main Authors: Marta Woźniak, Rafał Krajewski, Sebastian Makuch, Siddarth Agrawal
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
phytochemicals
gynecological cancers
anticancer
Online Access:https://www.mdpi.com/1422-0067/22/3/1219
id doaj-6b69ba36e2cb4653a7f779eb6ea4dacd
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spelling doaj-6b69ba36e2cb4653a7f779eb6ea4dacd2021-01-27T00:06:49ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-01-01221219121910.3390/ijms22031219Phytochemicals in Gynecological Cancer PreventionMarta Woźniak0Rafał Krajewski1Sebastian Makuch2Siddarth Agrawal3Department of Pathology, Wroclaw Medical University, 50-368 Wroclaw, PolandDepartment and Clinic of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Pathology, Wroclaw Medical University, 50-368 Wroclaw, PolandDepartment of Pathology, Wroclaw Medical University, 50-368 Wroclaw, PolandGynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. This literature review summarizes the current knowledge on the phytochemicals with proven antitumor activity, emphasizing their effectiveness and mechanism of action in gynecological cancer.https://www.mdpi.com/1422-0067/22/3/1219phytochemicalsgynecological cancersanticancer
collection DOAJ
language English
format Article
sources DOAJ
author Marta Woźniak
Rafał Krajewski
Sebastian Makuch
Siddarth Agrawal
spellingShingle Marta Woźniak
Rafał Krajewski
Sebastian Makuch
Siddarth Agrawal
Phytochemicals in Gynecological Cancer Prevention
International Journal of Molecular Sciences
phytochemicals
gynecological cancers
anticancer
author_facet Marta Woźniak
Rafał Krajewski
Sebastian Makuch
Siddarth Agrawal
author_sort Marta Woźniak
title Phytochemicals in Gynecological Cancer Prevention
title_short Phytochemicals in Gynecological Cancer Prevention
title_full Phytochemicals in Gynecological Cancer Prevention
title_fullStr Phytochemicals in Gynecological Cancer Prevention
title_full_unstemmed Phytochemicals in Gynecological Cancer Prevention
title_sort phytochemicals in gynecological cancer prevention
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1661-6596
1422-0067
publishDate 2021-01-01
description Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. This literature review summarizes the current knowledge on the phytochemicals with proven antitumor activity, emphasizing their effectiveness and mechanism of action in gynecological cancer.
topic phytochemicals
gynecological cancers
anticancer
url https://www.mdpi.com/1422-0067/22/3/1219
work_keys_str_mv AT martawozniak phytochemicalsingynecologicalcancerprevention
AT rafałkrajewski phytochemicalsingynecologicalcancerprevention
AT sebastianmakuch phytochemicalsingynecologicalcancerprevention
AT siddarthagrawal phytochemicalsingynecologicalcancerprevention
_version_ 1724321954369896448

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