Effect of 0.1&#x0025; ethacridine lactate on the vas deferens and human spermatozoa- (A preliminary report based on animal and <i> in vitro </i> experiments)

Ethacridine Lactate (0.1&#x0025;) has been tried in dogs to show it&#x2032;s safety by clinical and histopathological examination of vas at dif-ferent time intervals. Also in vitro titration was carried out with normal human semen and serially diluted ethacridine lactate. With this prelimina...

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Bibliographic Details
Main Authors: Kamat D, Bharucha E
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 1978-01-01
Series:Journal of Postgraduate Medicine
Online Access:http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1978;volume=24;issue=4;spage=214;epage=217;aulast=Kamat
Description
Summary:Ethacridine Lactate (0.1&#x0025;) has been tried in dogs to show it&#x2032;s safety by clinical and histopathological examination of vas at dif-ferent time intervals. Also in vitro titration was carried out with normal human semen and serially diluted ethacridine lactate. With this preliminary study, 0.1&#x0025; Ethacridine lactate was found to be safe and effective for flushing the distal vas at the time of vasectomy for producing immediate azoospermia. It was also found to cause instant immobilization and lysis of the spermatozoa.
ISSN:0022-3859
0972-2823