HLA-DQ distribution and risk assessment of celiac disease in a Spanish center

ABSTRACT Aims: celiac disease is a multisystem immune-mediated disease triggered by gluten in genetically susceptible individuals. The HLA-DQ2 and/or HLA-DQ8 heterodimers are encoded by the main genetic predisposing factors and their presence is required for the development of the immunological re...

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Bibliographic Details
Main Authors: Eva Martínez-Ojinaga, Manuel Molina, Isabel Polanco, Elena Urcelay, Concepción Núñez
Format: Article
Language:English
Published: Aran Ediciones
Series:Revista Espanola de Enfermedades Digestivas
Subjects:
HLA
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082018000700003&lng=en&tlng=en