Herbal Therapy for the Treatment of Acetaminophen-Associated Liver Injury: Recent Advances and Future Perspectives

Herbal Therapy for the Treatment of Acetaminophen-Associated Liver Injury: Recent Advances and Future Perspectives

Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury worldwide, and mitochondrial oxidative stress is considered the major event responsible for APAP-associated liver injury (ALI). Despite the identification of N-acetyl cysteine, a reactive oxygen species scavenger that is...

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Bibliographic Details
Main Authors: Ling Chang, Dongwei Xu, Jianjun Zhu, Guangbo Ge, Xiaoni Kong, Ying Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
herbal therapy
acetaminophen
liver injury
P450 enzyme
oxidative stress
gut microbiota
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00313/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00313/full

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