Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β–Smad3 Pathway

Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β–Smad3 Pathway

Follistatin (FST) is an endogenous protein that irreversibly inhibits TGF-β superfamily members and plays an anti-fibrotic role in other diseases. However, the role of FST in diabetic cardiomyopathy remains unclear. In this study, we investigated the effects of FST on diabetic cardiomyopathy. The ex...

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Bibliographic Details
Main Authors:	Yinhui Wang, Kun Yu, Chengcheng Zhao, Ling Zhou, Jia Cheng, Dao Wen Wang, Chunxia Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Series:	Frontiers in Pharmacology
Subjects:	follistatin diabetic cardiomyopathy fibrosis TGF-β hypertrophy
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.683335/full

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