Kinetic analysis of [18F] altanserin bolus injection in the canine brain using PET imaging

Kinetic analysis of [18F] altanserin bolus injection in the canine brain using PET imaging

Abstract Background Currently, [18F] altanserin is the most frequently used PET-radioligand for serotonin2A (5-HT2A) receptor imaging in the human brain but has never been validated in dogs. In vivo imaging of this receptor in the canine brain could improve diagnosis and therapy of several behaviour...

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Bibliographic Details
Main Authors: Glenn Pauwelyn, Lise Vlerick, Robrecht Dockx, Jeroen Verhoeven, Andre Dobbeleir, Tim Bosmans, Kathelijne Peremans, Christian Vanhove, Ingeborgh Polis, Filip De Vos
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Veterinary Research
Subjects:
Canine brain
Kinetic modelling
5HT2a receptor
Mood-disorders
Online Access:http://link.springer.com/article/10.1186/s12917-019-2165-5

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