Larger Numbers of Glial and Neuronal Cells in the Periaqueductal Gray Matter of μ-Opioid Receptor Knockout Mice

Larger Numbers of Glial and Neuronal Cells in the Periaqueductal Gray Matter of μ-Opioid Receptor Knockout Mice

Background: μ-opioid receptor knockout (MOP-KO) mice display baseline hyperalgesia. We have recently identified changes in tissue volume in the periaqueductal gray matter (PAG) using magnetic resonance imaging voxel-based morphometry. Changes in the structure and connectivity of this region might ac...

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Bibliographic Details
Main Authors: Kazumasu Sasaki, Frank Scott Hall, George R. Uhl, Ichiro Sora
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Psychiatry
Subjects:
μ opioid
μ opioid receptor knockout (MOP-KO)
periaqueductal gray matter (PAG)
microglia
astrocytes
neuron
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00441/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00441/full

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