Structural and Functional Properties of Subsidiary Atrial Pacemakers in a Goat Model of Sinus Node Disease

Structural and Functional Properties of Subsidiary Atrial Pacemakers in a Goat Model of Sinus Node Disease

BackgroundThe sinoatrial/sinus node (SAN) is the primary pacemaker of the heart. In humans, SAN is surrounded by the paranodal area (PNA). Although the PNA function remains debated, it is thought to act as a subsidiary atrial pacemaker (SAP) tissue and become the dominant pacemaker in the setting of...

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Bibliographic Details
Main Authors: Luca Soattin, Zoltan Borbas, Jane Caldwell, Brian Prendergast, Akbar Vohra, Yawer Saeed, Andreas Hoschtitzky, Joseph Yanni, Andrew Atkinson, Sunil Jit Logantha, Balint Borbas, Clifford Garratt, Gwilym Matthew Morris, Halina Dobrzynski
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
sinus node ablation
sinus node disease
subsidiary atrial pacemaker tissue
paranodal area
SND goat model
site of earliest activation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.592229/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.592229/full

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