Comparative Proteomic Analysis of Polarized Human THP-1 and Mouse RAW264.7 Macrophages

Comparative Proteomic Analysis of Polarized Human THP-1 and Mouse RAW264.7 Macrophages

Macrophages can be polarized into classically activated macrophages (M1) and alternatively activated macrophages (M2) in the immune system, performing pro-inflammatory and anti-inflammatory functions, respectively. Human THP-1 and mouse RAW264.7 cell line models have been widely used in various macr...

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Bibliographic Details
Main Authors: Pengfei Li, Zhifang Hao, Jingyu Wu, Chen Ma, Yintai Xu, Jun Li, Rongxia Lan, Bojing Zhu, Pengyu Ren, Daidi Fan, Shisheng Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
macrophage
polarization
cell model
proteomics
mass spectrometry
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.700009/full

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