CD147 Promotes Cell Small Extracellular Vesicles Release during Colon Cancer Stem Cells Differentiation and Triggers Cellular Changes in Recipient Cells

CD147 Promotes Cell Small Extracellular Vesicles Release during Colon Cancer Stem Cells Differentiation and Triggers Cellular Changes in Recipient Cells

Cancer cells secrete small extracellular vesicles (sEVs) that are involved in the remodeling of tumor microenvironment (TME) and can promote tumor progression. The role of sEVs and their molecular key players in colon cancer stem cells differentiation are poorly understood. This study aimed to analy...

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Bibliographic Details
Main Authors: Donatella Lucchetti, Filomena Colella, Luigi Perelli, Claudio Ricciardi-Tenore, Federica Calapà, Micol E. Fiori, Federica Carbone, Ruggero De Maria, Alessandro Sgambato
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
small extracellular vesicles
colorectal cancer stem cells
differentiation
cd147
Online Access:https://www.mdpi.com/2072-6694/12/2/260

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