Electophoretically Deposition of Ti3C2 on Titanium Surface for Hard Tissue Implant Applications

As a metallic biomaterial, titanium (Ti) exhibits excellent biocompatibility, but its osteoinductivity is limited. Therefore, to improve this property, an electrophoretic deposition (EPD) technique was used to coat the Ti surface with Ti3C2 MXene (Ti<...

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Main Authors:	Jun-Hwee Jang, Jun-Sung Oh, Eun-Jung Lee, Cheol-Min Han
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Coatings
Subjects:	MXene titanium electrophoretic deposition human mesenchymal stem cells
Online Access:	https://www.mdpi.com/2079-6412/11/7/761

id	doaj-6b19fcbfd88e4ecb90e0fdb0de93babf
record_format	Article
spelling	doaj-6b19fcbfd88e4ecb90e0fdb0de93babf2021-07-23T13:35:57ZengMDPI AGCoatings2079-64122021-06-011176176110.3390/coatings11070761Electophoretically Deposition of Ti<sub>3</sub>C<sub>2</sub> on Titanium Surface for Hard Tissue Implant ApplicationsJun-Hwee Jang0Jun-Sung Oh1Eun-Jung Lee2Cheol-Min Han3Department of Nano-Biomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, KoreaDepartment of Nano-Biomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, KoreaDepartment of Nano-Biomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, KoreaDepartment of Carbon and Nano Materials Engineering, Jeonju University, Jeonju 55069, KoreaAs a metallic biomaterial, titanium (Ti) exhibits excellent biocompatibility, but its osteoinductivity is limited. Therefore, to improve this property, an electrophoretic deposition (EPD) technique was used to coat the Ti surface with Ti<sub>3</sub>C<sub>2</sub> MXene (Ti<sub>3</sub>C<sub>2</sub>), a new class of two-dimensional nanomaterial. Ti<sub>3</sub>C<sub>2</sub> is known to have good biocompatibility and better osteoinductivity than graphene oxide. The coating layer was characterized by a particulate microstructure and exhibited X-ray diffraction and Raman spectroscopy peaks corresponding to the Ti<sub>3</sub>C<sub>2</sub> phase. In vitro cell tests using human mesenchymal stem cells confirmed that the cell attachment and proliferation on Ti<sub>3</sub>C<sub>2</sub>-coated Ti were similar to that of bare Ti, and that the osteoinductivity was significantly enhanced compared with bare Ti.https://www.mdpi.com/2079-6412/11/7/761MXenetitaniumelectrophoretic depositionhuman mesenchymal stem cells
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Jun-Hwee Jang Jun-Sung Oh Eun-Jung Lee Cheol-Min Han
spellingShingle	Jun-Hwee Jang Jun-Sung Oh Eun-Jung Lee Cheol-Min Han Electophoretically Deposition of Ti<sub>3</sub>C<sub>2</sub> on Titanium Surface for Hard Tissue Implant Applications Coatings MXene titanium electrophoretic deposition human mesenchymal stem cells
author_facet	Jun-Hwee Jang Jun-Sung Oh Eun-Jung Lee Cheol-Min Han
author_sort	Jun-Hwee Jang
title	Electophoretically Deposition of Ti<sub>3</sub>C<sub>2</sub> on Titanium Surface for Hard Tissue Implant Applications
title_short	Electophoretically Deposition of Ti<sub>3</sub>C<sub>2</sub> on Titanium Surface for Hard Tissue Implant Applications
title_full	Electophoretically Deposition of Ti<sub>3</sub>C<sub>2</sub> on Titanium Surface for Hard Tissue Implant Applications
title_fullStr	Electophoretically Deposition of Ti<sub>3</sub>C<sub>2</sub> on Titanium Surface for Hard Tissue Implant Applications
title_full_unstemmed	Electophoretically Deposition of Ti<sub>3</sub>C<sub>2</sub> on Titanium Surface for Hard Tissue Implant Applications
title_sort	electophoretically deposition of ti<sub>3</sub>c<sub>2</sub> on titanium surface for hard tissue implant applications
publisher	MDPI AG
series	Coatings
issn	2079-6412
publishDate	2021-06-01
description	As a metallic biomaterial, titanium (Ti) exhibits excellent biocompatibility, but its osteoinductivity is limited. Therefore, to improve this property, an electrophoretic deposition (EPD) technique was used to coat the Ti surface with Ti<sub>3</sub>C<sub>2</sub> MXene (Ti<sub>3</sub>C<sub>2</sub>), a new class of two-dimensional nanomaterial. Ti<sub>3</sub>C<sub>2</sub> is known to have good biocompatibility and better osteoinductivity than graphene oxide. The coating layer was characterized by a particulate microstructure and exhibited X-ray diffraction and Raman spectroscopy peaks corresponding to the Ti<sub>3</sub>C<sub>2</sub> phase. In vitro cell tests using human mesenchymal stem cells confirmed that the cell attachment and proliferation on Ti<sub>3</sub>C<sub>2</sub>-coated Ti were similar to that of bare Ti, and that the osteoinductivity was significantly enhanced compared with bare Ti.
topic	MXene titanium electrophoretic deposition human mesenchymal stem cells
url	https://www.mdpi.com/2079-6412/11/7/761
work_keys_str_mv	AT junhweejang electophoreticallydepositionoftisub3subcsub2subontitaniumsurfaceforhardtissueimplantapplications AT junsungoh electophoreticallydepositionoftisub3subcsub2subontitaniumsurfaceforhardtissueimplantapplications AT eunjunglee electophoreticallydepositionoftisub3subcsub2subontitaniumsurfaceforhardtissueimplantapplications AT cheolminhan electophoreticallydepositionoftisub3subcsub2subontitaniumsurfaceforhardtissueimplantapplications
_version_	1721288894506336256

Electophoretically Deposition of Ti<sub>3</sub>C<sub>2</sub> on Titanium Surface for Hard Tissue Implant Applications

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